本卷提供了RNA生物信息学方法的概述，包括预测二级和三级结构的基本策略，以及基于大规模RNA测序的新算法。由于近期高通量测序技术的发展，科学家们可以在单核苷酸分辨率下研究完整的转录组，因此对RNA生物信息学的兴趣迅速增加。采用先进的计算技术，科学家们现在能够进行更深入的研究，并在本书中向大家介绍。本书采用非常成功的《分子生物学方法》系列格式编写，各章内容包括各自主题的介绍、必要的材料和设备清单、逐步的、易于重复的生物信息学方案，以及避免已知陷阱的关键提示。

《RNA生物信息学》具有权威性和实用性，旨在帮助科学家进一步研究RNA的生物信息学和计算生物学。

This volumeprovides an overview of RNA bioinformatics methodologies, including basic strategies to predict secondary and tertiary structures, and novel algorithms based on massive RNA sequencing. Interest in RNA bioinformatics has rapidly increased thanks to the recent high-throughput sequencing technologies allowing scientists to investigate complete transcriptomes at single nucleotide resolution. Adopting advanced computational technics, scientists are now able to conduct more in-depth studies and present them to you in this book. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and equipment, step-by-step, readily reproducible bioinformatics protocols, and key tips to avoid known pitfalls.

Authoritative and practical, RNA Bioinformatics seeks to aid scientists in the further study of bioinformatics and computational biology of RNA.